RPA3

Across TCGA cell cohorts, RPA3 protein abundance is significantly associated with the RNA expression of many other genes, with 8,699 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible RPA3-associated genes across cancer lineages are DNAJC3, TM9SF2, and STK24. Each is linked with RPA3 in more than 14 cancer types. Because this analysis shows association rather than direction, both RPA3-to-partner and partner-to-RPA3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, RPA3 versus DNAJC3 in LUNG_SCLC, with a Pearson correlation of 0.76.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RPA3→partner) and Y-score (partner→RPA3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	DNAJC3 →	+1.274	+1.082	<.001	<.001	3	15
LUNG_NSCLC_LUAD	TM9SF2 →	+1.404	+0.944	<.001	<.001	3	11
OVARY	STK24 →	+1.344	+1.495	<.001	<.001	3	10
STOMACH	UGGT2 →	+1.351	+1.335	.002	<.001	3	10
URINARY_TRACT	ELF1 →	+1.051	+0.762	<.001	<.001	3	9
LUNG_NSCLC_LUAD	TGDS →	+1.008	+0.700	.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,699 associations by consensus.

RPA3 vs DNAJC3 — LUNG_SCLC

Explore this scatter interactively →