RPA2P3

Across TCGA pan-cancer cohorts, RPA2P3 RNA is linked to patient survival in 14 of 34 cancer types, making it the most broadly survival-associated RPA2P3 data layer.

The strongest signal is observed in mesothelioma (MESO), where higher RPA2P3 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated RPA2P3 expression acts as an unfavorable survival marker, although some lineages such as KIRC and OV show a favorable association.

MESO, COAD, and KIRC are the cancer types where RPA2P3 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
MESO	OS	Tertile	II,III,IV	0.172	0.584	<.001	63	view →
COAD	OS	Tertile	All	0.675	0.844	.005	34	view →
KIRC	DFS	Tertile	II,III,IV	0.728	0.492	.013	30	view →
SKCM	DFS	Tertile	IV	0.036	0.433	<.001	27	view →
ACC	OS	Tertile	IV	0.327	0.633	.045	18	view →
UCEC	OS	Median	All	0.596	0.734	.019	12	view →
OV	DFS	Median	IV	0.606	0.357	.007	10	view →
LAML	DFS	Quartile	All	0.674	0.321	.035	10	view →
STAD	OS	Median	II,III,IV	0.447	0.668	.007	9	view →
LIHC	DFS	Tertile	All	0.187	0.451	.018	9	view →
LUAD	DFS	Tertile	All	0.791	0.643	.028	9	view →
ESCA	OS	Median	II,III,IV	0.586	1.000	.036	6	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 14 lineages.

RPA2P3–MESO (OS)

Open the MESO breakdown →