RPA2

RNA expression — cross-omics
Cross-omicsRNA → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, RPA2 RNA expression is significantly associated with the protein abundance of many other proteins, with 9,597 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible RPA2-associated proteins across cancer lineages are RPA1, RPA3, and DNAJC8. Each is linked with RPA2 in more than 6 cancer types. Because this analysis shows association rather than direction, both RPA2-to-partner and partner-to-RPA2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, RPA2 versus RPA1 in GBM, with a Pearson correlation of 0.51.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (RPA2→partner) and Y-score (partner→RPA2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
GBMRPA1 →+0.307+0.309<.001<.00137
OVRPA3 →+0.340+0.505.002<.00136
GBMDNAJC8 →+0.338+0.374<.001<.00136
COADNUDC →+0.312+0.347<.001<.00136
OVRPS6KA1 →+0.398+0.512.001.00235
GBMYTHDF2 →+0.345+0.419<.001<.00135
Each partner links to its Q-omics profile. Showing the 6 strongest of 9,597 associations by consensus.

RPA2 vs RPA1 — GBM

Per-sample scatter of RPA2 vs RPA1 in GBM (Pearson r = 0.51).

Explore this scatter interactively →

Exploration