RPA2

Across TCGA patient cohorts, RPA2 protein abundance is significantly associated with the RNA expression of many other genes, with 19,685 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible RPA2-associated genes across cancer lineages are SRSF10, GPN2, and ITGB3BP. Each is linked with RPA2 in more than 6 cancer types. Because this analysis shows association rather than direction, both RPA2-to-partner and partner-to-RPA2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, RPA2 versus SRSF10 in UCEC, with a Pearson correlation of 0.36.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RPA2→partner) and Y-score (partner→RPA2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	SRSF10 →	+0.479	+0.299	<.001	<.001	3	7
OV	GPN2 →	+0.577	+0.369	<.001	.004	3	6
GBM	ITGB3BP →	+0.676	+0.406	<.001	<.001	3	6
LSCC	LZIC →	+0.550	+0.340	<.001	<.001	3	6
OV	RBBP4 →	+0.464	+0.319	<.001	.001	3	6
UCEC	ZNF232 →	+0.805	+0.218	.009	.005	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 19,685 associations by consensus.

RPA2 vs SRSF10 — UCEC

Explore this scatter interactively →