RPA1

Across TCGA patient cohorts, RPA1 RNA expression is significantly associated with the protein abundance of many other proteins, with 15,437 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible RPA1-associated proteins across cancer lineages are ELAC2, SPAG7, and GATAD2B. Each is linked with RPA1 in more than 7 cancer types. Because this analysis shows association rather than direction, both RPA1-to-partner and partner-to-RPA1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, RPA1 versus ELAC2 in OV, with a Pearson correlation of 0.39.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (RPA1→partner) and Y-score (partner→RPA1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	ELAC2 →	+0.435	+0.562	.001	.002	3	8
BRCA	SPAG7 →	+0.316	+0.539	<.001	<.001	3	7
LSCC	GATAD2B →	+0.274	+0.467	<.001	<.001	3	7
LSCC	ALKBH5 →	+0.541	+0.855	<.001	<.001	3	7
GBM	MCM4 →	+0.788	+0.410	<.001	<.001	3	7
LSCC	SNRNP200 →	+0.249	+0.700	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,437 associations by consensus.

RPA1 vs ELAC2 — OV

Explore this scatter interactively →