RPA1

Across TCGA cell cohorts, RPA1 protein abundance is significantly associated with the RNA expression of many other genes, with 4,958 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible RPA1-associated genes across cancer lineages are KLF5, LGR4, and GRTP1. Each is linked with RPA1 in more than 4 cancer types. Because this analysis shows association rather than direction, both RPA1-to-partner and partner-to-RPA1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, RPA1 versus KLF5 in LARGE_INTESTINE, with a Pearson correlation of 0.45.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RPA1→partner) and Y-score (partner→RPA1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	KLF5 →	+0.968	+0.843	<.001	<.001	3	5
LUNG_NSCLC_LUAD	LGR4 →	+1.317	+1.259	.007	<.001	3	4
PANCREAS	GRTP1 →	+1.975	+0.692	<.001	<.001	3	3
OVARY	MESD →	+0.901	+1.150	<.001	.003	3	3
OVARY	FGD3 →	-1.790	-1.132	<.001	.004	3	3
STOMACH	TSPO →	+1.181	+0.898	.009	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,958 associations by consensus.

RPA1 vs KLF5 — LARGE_INTESTINE

Explore this scatter interactively →