Across TCGA patient cohorts, RP1L1 mutation is significantly associated with the RNA expression of many other genes, with 9,184 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RP1L1-associated genes across cancer lineages are CDCA2, SASS6, and FAM136A. Each is linked with RP1L1 in more than 6 cancer types. Because this analysis shows association rather than direction, both RP1L1-to-partner and partner-to-RP1L1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RP1L1→partner) and Y-score (partner→RP1L1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	CDCA2 →	+0.730	+2.125	<.001	<.001	3	7
LUAD	SASS6 →	+0.495	+1.765	<.001	<.001	3	6
LUAD	FAM136A →	+0.262	+2.074	<.001	<.001	3	6
COAD	ERI1 →	+0.587	+2.598	<.001	<.001	3	6
UCEC	TAF9 →	+0.635	+2.125	<.001	<.001	3	5
UCEC	BUB3 →	+0.372	+1.304	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,184 associations by consensus.

Exploration

RP1L1 survival (RNA) · tumor vs normal (RNA) · all RP1L1 data types