Across TCGA patient cohorts, RP1L1 mutation is significantly associated with the total protein of many other genes, with 81 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RP1L1-associated genes across cancer lineages are 4E-BP1, Caspase-7-cleavedD198, and Rictor. Each is linked with RP1L1 in more than 5 cancer types. Because this analysis shows association rather than direction, both RP1L1-to-partner and partner-to-RP1L1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RP1L1→partner) and Y-score (partner→RP1L1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	4E-BP1 →	+0.332	+3.000	.007	.034	2	6
STAD	Caspase-7-cleavedD198 →	+0.698	+3.000	.025	.034	3	4
COAD	Rictor →	-0.836	-1.807	.007	.024	3	4
UCEC	eIF4E →	+0.185	+4.183	.001	<.001	3	4
STAD	Caveolin-1 →	-0.795	-2.584	.011	.010	3	3
UCEC	Cyclin-B1 →	+0.476	+1.343	.001	.002	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 81 associations by consensus.

Exploration

RP1L1 survival (RNA) · tumor vs normal (RNA) · all RP1L1 data types