Across TCGA cell cohorts, RP1L1 mutation is significantly associated with the RNA expression of many other genes, with 1,206 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible RP1L1-associated genes across cancer lineages are TTC39B, TTC39C, and FOCAD. Each is linked with RP1L1 in more than 2 cancer types. Because this analysis shows association rather than direction, both RP1L1-to-partner and partner-to-RP1L1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RP1L1→partner) and Y-score (partner→RP1L1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	TTC39B →	+0.896	+2.700	<.001	.002	3	3
LARGE_INTESTINE	TTC39C →	+0.861	+3.409	<.001	<.001	3	3
LARGE_INTESTINE	FOCAD →	+0.789	+2.700	<.001	.001	3	3
LARGE_INTESTINE	GAN →	+0.437	+1.949	.006	.002	3	3
OESOPHAGUS	BRDT →	+2.087	+3.399	.004	.006	3	2
BLOOD_Leukemia	NEXMIF →	+0.319	+2.614	.005	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,206 associations by consensus.

Exploration

RP1L1 survival (RNA) · tumor vs normal (RNA) · all RP1L1 data types