RORC

Across TCGA patient cohorts, RORC protein abundance is significantly associated with the RNA expression of many other genes, with 330 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible RORC-associated genes across cancer lineages are UPK3A, CSTF1, and MTG2. Each is linked with RORC in more than 1 cancer types. Because this analysis shows association rather than direction, both RORC-to-partner and partner-to-RORC results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, RORC versus UPK3A in LUAD, with a Pearson correlation of -0.62.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RORC→partner) and Y-score (partner→RORC) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	UPK3A →	-1.654	-1.114	<.001	<.001	3	1
LUAD	CSTF1 →	-0.696	-1.027	.005	.001	3	1
LUAD	MTG2 →	-0.987	-0.994	.002	.001	3	1
LUAD	NDRG4 →	-0.798	-0.824	.001	.004	3	1
LUAD	NAGPA →	-0.336	-0.898	.003	<.001	3	1
LUAD	CLCN7 →	-0.754	-0.898	.005	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 330 associations by consensus.

RORC vs UPK3A — LUAD

Explore this scatter interactively →