Across TCGA patient cohorts, RORB mutation is significantly associated with the RNA expression of many other genes, with 4,463 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RORB-associated genes across cancer lineages are CHCHD4, ENTR1, and CHAF1A. Each is linked with RORB in more than 2 cancer types. Because this analysis shows association rather than direction, both RORB-to-partner and partner-to-RORB results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RORB→partner) and Y-score (partner→RORB) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	CHCHD4 →	+0.376	+2.194	<.001	.001	3	3
UCEC	ENTR1 →	+0.505	+2.101	<.001	<.001	3	3
UCEC	CHAF1A →	+0.902	+3.879	<.001	<.001	3	3
COAD	MIR4710 →	+0.333	+3.187	.001	.006	3	3
UCEC	MYO19 →	+0.478	+2.971	<.001	<.001	3	3
UCEC	ATP2A1-AS1 →	+0.918	+2.091	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,463 associations by consensus.

Exploration

RORB survival (RNA) · tumor vs normal (RNA) · all RORB data types