RORA

Across TCGA patient cohorts, RORA protein abundance is significantly associated with the RNA expression of many other genes, with 9,880 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible RORA-associated genes across cancer lineages are SEMA3G, MEIS3, and SGCA. Each is linked with RORA in more than 1 cancer types. Because this analysis shows association rather than direction, both RORA-to-partner and partner-to-RORA results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, RORA versus SEMA3G in BRCA, with a Pearson correlation of 0.41.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RORA→partner) and Y-score (partner→RORA) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	SEMA3G →	+1.509	+0.664	<.001	<.001	3	2
BRCA	MEIS3 →	+1.913	+1.033	<.001	<.001	3	2
UCEC	SGCA →	+0.869	+0.332	.005	.002	3	2
UCEC	SOD3 →	+1.714	+0.479	<.001	<.001	3	2
UCEC	ABCG2 →	+1.363	+0.320	.004	.005	3	2
BRCA	MYCT1 →	+1.190	+0.775	.002	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,880 associations by consensus.

RORA vs SEMA3G — BRCA

Explore this scatter interactively →