Across TCGA patient cohorts, ROR1 RNA expression is significantly associated with the protein abundance of many other proteins, with 18,573 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible ROR1-associated proteins across cancer lineages are YME1L1, C11orf68, and SEPTIN7. Each is linked with ROR1 in more than 6 cancer types. Because this analysis shows association rather than direction, both ROR1-to-partner and partner-to-ROR1 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ROR1→partner) and Y-score (partner→ROR1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	YME1L1 →	-0.301	-1.205	<.001	<.001	3	7
UCEC	C11orf68 →	+0.256	+0.792	.003	.005	3	7
PDAC	SEPTIN7 →	+0.284	+0.516	<.001	<.001	3	6
PDAC	TOMM5 →	-0.473	-0.371	<.001	.007	3	6
BRCA	CAVIN3 →	+0.741	+0.722	<.001	<.001	3	6
BRCA	CLPX →	-0.321	-0.819	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 18,573 associations by consensus.

Exploration

ROR1 survival (RNA) · tumor vs normal (RNA) · all ROR1 data types