Across TCGA patient cohorts, ROR1 protein abundance is significantly associated with the RNA expression of many other genes, with 8,136 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible ROR1-associated genes across cancer lineages are CRISPLD2, EPAS1, and RARRES2. Each is linked with ROR1 in more than 3 cancer types. Because this analysis shows association rather than direction, both ROR1-to-partner and partner-to-ROR1 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ROR1→partner) and Y-score (partner→ROR1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	CRISPLD2 →	+1.327	+0.347	<.001	.002	3	4
GBM	EPAS1 →	+0.819	+0.907	<.001	<.001	3	4
OV	RARRES2 →	+1.368	+0.411	<.001	.004	3	3
OV	MGP →	+1.471	+0.487	<.001	<.001	3	3
GBM	VDR →	+1.311	+0.862	<.001	<.001	3	3
CCRCC	FOXP1 →	+0.450	+0.756	.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,136 associations by consensus.

Exploration

ROR1 survival (RNA) · tumor vs normal (RNA) · all ROR1 data types