ROPN1L

Across TCGA pan-cancer cohorts, ROPN1L mass-spec protein is linked to patient survival in 2 of 34 cancer types, making it a survival-associated ROPN1L data layer compared with 23 for mass-spec protein.

The strongest signal is observed in lung squamous cell carcinoma (LSCC), where higher ROPN1L mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated ROPN1L expression acts as an unfavorable survival marker, although some lineages such as LSCC show a favorable association.

LSCC and LUAD are the cancer types where ROPN1L mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LSCC	DFS	Median	III,IV	0.930	0.411	.002	9	view →
LUAD	DFS	Tertile	III,IV	0.403	0.854	.033	4	view →

Pink = unfavorable, green = favorable. Showing the 2 strongest of 2 lineages.

ROPN1L–LSCC (DFS)

Open the LSCC breakdown →