ROMO1

Across TCGA patient cohorts, ROMO1 mutation is significantly associated with the RNA expression of many other genes, with 3 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible ROMO1-associated genes across cancer lineages are RBMY1HP, RNU6-452P, and MIR378E. Each is linked with ROMO1 in more than 1 cancer types. Because this analysis shows association rather than direction, both ROMO1-to-partner and partner-to-ROMO1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RBMY1HP grouped by ROMO1-low versus ROMO1-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ROMO1→partner) and Y-score (partner→ROMO1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	RBMY1HP →	+0.039	+7.816	<.001	.008	3	1
SKCM	RNU6-452P →	+0.868	+7.816	<.001	.008	3	1
UCEC	MIR378E →	+0.760	+5.453	<.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

RBMY1HP by ROMO1 expression — SKCM

Explore this box plot interactively →