ROGDI

Across TCGA cell cohorts, ROGDI RNA expression is significantly associated with the go_rna of many other GO terms, with 4,261 significant associations in total. BONE shows the largest number of these associations.

The most reproducible ROGDI-associated GO terms across cancer lineages are Negative regulation of calcium ion export across plasma membrane, Cilium movement involved in cell motility, and Vacuolar acidification. Each is linked with ROGDI in more than 14 cancer types. Because this analysis shows association rather than direction, both ROGDI-to-partner and partner-to-ROGDI results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of calcium ion export across plasma membrane grouped by ROGDI-low versus ROGDI-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ROGDI→partner) and Y-score (partner→ROGDI) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Negative regulation of calcium ion export across plasma membrane →	+0.057	+0.859	<.001	<.001	3	15
UPPER_AERODIGESTIVE_TRACT	Cilium movement involved in cell motility →	-0.094	-0.906	<.001	<.001	3	14
STOMACH	Vacuolar acidification →	+0.175	+1.355	<.001	<.001	3	14
STOMACH	Regulation of proteasomal protein catabolic process →	+0.077	+1.297	<.001	<.001	3	14
STOMACH	Calcium-independent cell-matrix adhesion →	+0.209	+1.070	<.001	<.001	3	14
UPPER_AERODIGESTIVE_TRACT	Cilium or flagellum-dependent cell motility →	-0.091	-0.906	<.001	<.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,261 associations by consensus.

Negative regulation of calcium ion export across plasma membrane by ROGDI expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →