Across TCGA patient cohorts, ROBO2 RNA expression is significantly associated with the protein abundance of many other proteins, with 22,474 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible ROBO2-associated proteins across cancer lineages are THEMIS2, CENPV, and DTX3L_S539. Each is linked with ROBO2 in more than 7 cancer types. Because this analysis shows association rather than direction, both ROBO2-to-partner and partner-to-ROBO2 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ROBO2→partner) and Y-score (partner→ROBO2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	THEMIS2 →	-0.428	-1.258	<.001	<.001	3	8
LUAD	CENPV →	+0.653	+1.037	<.001	<.001	3	7
LSCC	DTX3L_S539 →	-0.504	-0.621	<.001	.003	3	7
BRCA	EPM2AIP1 →	+0.461	+0.988	.001	<.001	3	7
GBM	TYMP_S50 →	-0.734	-2.064	.004	.002	3	6
LUAD	RPL5 →	-0.224	-0.861	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 22,474 associations by consensus.

Exploration

ROBO2 survival (RNA) · tumor vs normal (RNA) · all ROBO2 data types