ROBO1

Across TCGA cell cohorts, ROBO1 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,734 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible ROBO1-associated GO terms across cancer lineages are Cerebral cortex tangential migration, Olfactory bulb interneuron development, and Olfactory bulb interneuron differentiation. Each is linked with ROBO1 in more than 18 cancer types. Because this analysis shows association rather than direction, both ROBO1-to-partner and partner-to-ROBO1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Cerebral cortex tangential migration grouped by ROBO1-low versus ROBO1-high in BLOOD_Myeloma.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ROBO1→partner) and Y-score (partner→ROBO1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Myeloma	Cerebral cortex tangential migration →	+1.938	+3.930	<.001	<.001	3	19
STOMACH	Olfactory bulb interneuron development →	+2.075	+4.399	<.001	<.001	3	19
STOMACH	Olfactory bulb interneuron differentiation →	+2.109	+4.539	<.001	<.001	3	18
LUNG_NSCLC_LUSC	Negative regulation of negative chemotaxis →	+1.706	+3.715	<.001	<.001	3	17
LUNG_NSCLC_LUSC	Negative regulation of mammary gland epithelial cell proliferation →	+1.624	+3.798	<.001	<.001	3	16
BLOOD_Myeloma	Regulation of negative chemotaxis →	+1.821	+4.106	<.001	<.001	3	16

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,734 associations by consensus.

Cerebral cortex tangential migration by ROBO1 expression — BLOOD_Myeloma

Explore this box plot interactively →