RO60

Across TCGA patient cohorts, RO60 mutation is significantly associated with the RNA expression of many other genes, with 1,877 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RO60-associated genes across cancer lineages are RN7SL504P, RNU1-20P, and LINC01400. Each is linked with RO60 in more than 1 cancer types. Because this analysis shows association rather than direction, both RO60-to-partner and partner-to-RO60 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RN7SL504P grouped by RO60-low versus RO60-high in PRAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RO60→partner) and Y-score (partner→RO60) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PRAD	RN7SL504P →	+0.198	+6.921	<.001	<.001	3	2
SKCM	RNU1-20P →	+0.300	+5.513	.001	.004	3	2
SKCM	LINC01400 →	+0.057	+5.037	<.001	.009	3	2
CESC	MAGEA9 →	+0.193	+5.127	<.001	.001	3	2
CESC	KRTAP1-4 →	+0.178	+6.164	<.001	<.001	3	2
UCEC	CHAF1A →	+0.649	+2.960	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,877 associations by consensus.

RN7SL504P by RO60 expression — PRAD

Explore this box plot interactively →