RO60

Across TCGA cell cohorts, RO60 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,845 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible RO60-associated GO terms across cancer lineages are Positive regulation of mRNA processing, Negative regulation of gene expression, epigenetic, and Positive regulation of organelle assembly. Each is linked with RO60 in more than 15 cancer types. Because this analysis shows association rather than direction, both RO60-to-partner and partner-to-RO60 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of mRNA processing grouped by RO60-low versus RO60-high in SKIN.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RO60→partner) and Y-score (partner→RO60) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	Positive regulation of mRNA processing →	+0.118	+0.852	<.001	<.001	3	15
STOMACH	Negative regulation of gene expression, epigenetic →	+0.074	+0.508	.001	.004	3	15
STOMACH	Positive regulation of organelle assembly →	+0.078	+0.805	<.001	.004	2	16
STOMACH	Epigenetic regulation of gene expression →	+0.075	+0.809	<.001	.002	3	14
STOMACH	Protein modification by small protein removal →	+0.048	+0.602	.002	.009	3	14
STOMACH	Protein deubiquitination →	+0.054	+0.852	.002	.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,845 associations by consensus.

Positive regulation of mRNA processing by RO60 expression — SKIN

Explore this box plot interactively →