Across TCGA pan-cancer cohorts, RNY4P7 RNA differs between tumor and matched normal tissue in 1 of 18 cancer types tested, making tumor–normal expression one of RNY4P7’s most consistent transcriptional readouts.
The strongest signal is observed in kidney renal papillary cell carcinoma (KIRP), where RNY4P7 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types RNY4P7 is over-expressed in tumor.
KIRP are the cancer types where RNY4P7 tumor–normal differential expression is most reproducible.