Across TCGA pan-cancer cohorts, RNY4P6 RNA differs between tumor and matched normal tissue in 4 of 18 cancer types tested, making tumor–normal expression one of RNY4P6’s most consistent transcriptional readouts.

The strongest signal is observed in breast invasive carcinoma (BRCA), where RNY4P6 RNA is repressed in tumor relative to normal tissue. In most cancer types RNY4P6 is over-expressed in tumor, although a few such as BRCA and STAD show the opposite, repressed pattern.

BRCA, STAD, and THCA are the cancer types where RNY4P6 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in RNY4P6 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
BRCA	All	III,IV	−0.383	.028	2	view →
STAD	All	IV	−1.193	.032	1	view →
THCA	All	IV	−0.449	.027	1	view →
LUSC	All	All	−0.233	.014	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 4 strongest of 4 lineages.

Exploration

Same gene, other analysis: RNY4P6 RNA expression & survival · all RNY4P6 data types