RNY4P25

Across TCGA pan-cancer cohorts, RNY4P25 RNA is linked to patient survival in 15 of 34 cancer types, making it the most broadly survival-associated RNY4P25 data layer.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher RNY4P25 RNA is associated with better disease-free survival. In most high-consensus cancer types, elevated RNY4P25 expression acts as an unfavorable survival marker, although some lineages such as HNSC and LUAD show a favorable association.

HNSC, CESC, and BRCA are the cancer types where RNY4P25 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
HNSC	DFS	Tertile	All	0.791	0.665	.006	75	view →
CESC	DFS	Quartile	III,IV	0.362	0.736	.002	54	view →
BRCA	OS	Tertile	All	0.533	0.645	.002	31	view →
LUAD	OS	Tertile	All	0.871	0.782	.002	31	view →
COAD	OS	Tertile	II,III,IV	0.396	0.600	.003	30	view →
MESO	OS	Tertile	III,IV	0.204	0.619	.006	27	view →
ACC	OS	Tertile	IV	0.327	0.633	.045	18	view →
UCEC	OS	Tertile	IV	0.277	0.638	.006	18	view →
SKCM	DFS	Tertile	IV	0.040	0.432	.038	12	view →
PRAD	DFS	Median	All	0.967	0.910	.002	12	view →
PAAD	OS	Median	II,III,IV	0.451	0.276	.028	8	view →
LGG	OS	Median	All	0.865	0.944	.008	6	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 15 lineages.

RNY4P25–HNSC (DFS)

Open the HNSC breakdown →