Across TCGA pan-cancer cohorts, RNY4P17 RNA differs between tumor and matched normal tissue in 2 of 18 cancer types tested, making tumor–normal expression one of RNY4P17’s most consistent transcriptional readouts.
The strongest signal is observed in stomach adenocarcinoma (STAD), where RNY4P17 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types RNY4P17 is over-expressed in tumor.
STAD and ESCA are the cancer types where RNY4P17 tumor–normal differential expression is most reproducible.