Across TCGA pan-cancer cohorts, RNY3P7 RNA differs between tumor and matched normal tissue in 4 of 18 cancer types tested, making tumor–normal expression one of RNY3P7’s most consistent transcriptional readouts.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where RNY3P7 RNA is repressed in tumor relative to normal tissue. In most cancer types RNY3P7 is over-expressed in tumor, although a few such as HNSC and LUSC show the opposite, repressed pattern.

HNSC, LUSC, and LUAD are the cancer types where RNY3P7 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in RNY3P7 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
HNSC	All	All	−0.257	<.001	8	view →
LUSC	All	All	−0.186	.006	2	view →
LUAD	Female	II,III,IV	−0.543	.014	1	view →
STAD	All	II,III,IV	−0.470	.036	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 4 strongest of 4 lineages.

Exploration

Same gene, other analysis: RNY3P7 RNA expression & survival · all RNY3P7 data types