Across TCGA pan-cancer cohorts, RNY3P11 RNA differs between tumor and matched normal tissue in 2 of 18 cancer types tested, making tumor–normal expression one of RNY3P11’s most consistent transcriptional readouts.
The strongest signal is observed in stomach adenocarcinoma (STAD), where RNY3P11 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types RNY3P11 is over-expressed in tumor.
STAD and LUSC are the cancer types where RNY3P11 tumor–normal differential expression is most reproducible.