RNY1P4

RNA & survival
SurvivalRNAKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, RNY1P4 RNA is linked to patient survival in 19 of 34 cancer types, making it the most broadly survival-associated RNY1P4 data layer.

The strongest signal is observed in uveal melanoma (UVM), where higher RNY1P4 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated RNY1P4 expression acts as an unfavorable survival marker, although some lineages such as UCS and LIHC show a favorable association.

UVM, UCS, and OV are the cancer types where RNY1P4 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
UVMOSTertileIII,IV0.3010.830<.00169view →
UCSOSMedianIV0.7320.224.01824view →
OVOSTertileAll0.2590.346.02424view →
LIHCOSTertileIII,IV1.0000.647.01721view →
ACCOSTertileIV0.3270.633.04518view →
LAMLDFSQuartileAll0.6550.339.01518view →
GBMDFSTertileAll0.1840.278.01815view →
SKCMDFSTertileIV0.9430.159.0319view →
STADDFSMedianAll0.3420.612.0178view →
PAADOSMedianAll0.4980.230.0028view →
LGGDFSQuartileAll0.6410.766.0097view →
LUSCDFSQuartileAll0.2820.433.0147view →
Pink = unfavorable, green = favorable. Showing the 12 strongest of 19 lineages.

Exploration