RNVU1-4

RNA & survival
SurvivalRNAKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, RNVU1-4 RNA is linked to patient survival in 25 of 34 cancer types, making it the most broadly survival-associated RNVU1-4 data layer.

The strongest signal is observed in rectum adenocarcinoma (READ), where higher RNVU1-4 RNA is associated with better overall survival. In most high-consensus cancer types, elevated RNVU1-4 expression acts as an unfavorable survival marker, although some lineages such as READ and KIRP show a favorable association.

READ, ACC, and KIRP are the cancer types where RNVU1-4 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
READOSQuartileII,III,IV0.8760.291<.00170view →
ACCOSMedianAll0.2990.753<.00169view →
KIRPOSMedianAll0.9660.839<.00146view →
LUSCOSQuartileII,III,IV0.6330.796.00327view →
BLCAOSTertileAll0.7490.511.01127view →
LGGDFSMedianAll0.6750.796.00127view →
OVOSTertileAll0.7980.880.01426view →
LAMLDFSTertileAll0.6820.311.00224view →
ESCAOSTertileAll0.5710.819.00219view →
LUADDFSMedianIV0.2700.807.00318view →
PRADDFSTertileAll0.8280.935<.00116view →
GBMDFSTertileAll0.1880.316.01613view →
Pink = unfavorable, green = favorable. Showing the 12 strongest of 25 lineages.

RNVU1-4–READ (OS)

Kaplan–Meier survival curve for RNVU1-4 RNA-high vs -low samples in READ.

Open the READ breakdown →

Exploration