RNVU1-28

Across TCGA pan-cancer cohorts, RNVU1-28 RNA differs between tumor and matched normal tissue in 6 of 18 cancer types tested, making tumor–normal expression one of RNVU1-28’s most consistent transcriptional readouts.

The strongest signal is observed in thyroid carcinoma (THCA), where RNVU1-28 RNA is repressed in tumor relative to normal tissue. In most cancer types RNVU1-28 is over-expressed in tumor, although a few such as THCA and BRCA show the opposite, repressed pattern.

THCA, COAD, and UCEC are the cancer types where RNVU1-28 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in RNVU1-28 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
THCA	All	II,III,IV	−0.642	<.001	7	view →
COAD	All	All	+0.418	.007	4	view →
UCEC	All	All	+0.357	.044	2	view →
BRCA	All	III,IV	−0.053	.049	2	view →
LUAD	All	All	+0.371	.046	1	view →
KIRP	All	All	+0.079	.028	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 6 strongest of 6 lineages.

RNVU1-28–THCA

Open the THCA breakdown →