RNVU1-27

RNA & survival
SurvivalRNAKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, RNVU1-27 RNA is linked to patient survival in 26 of 34 cancer types, making it the most broadly survival-associated RNVU1-27 data layer.

The strongest signal is observed in kidney chromophobe (KICH), where higher RNVU1-27 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated RNVU1-27 expression acts as an unfavorable survival marker, although some lineages such as SKCM and STAD show a favorable association.

KICH, KIRC, and ESCA are the cancer types where RNVU1-27 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
KICHDFSQuartileAll0.5261.000.00161view →
KIRCDFSQuartileAll0.7370.841.00354view →
ESCAOSQuartileIII,IV0.3410.804<.00151view →
LGGDFSMedianAll0.6770.797<.00145view →
COADDFSTertileIV0.3230.724.00143view →
SKCMOSQuartileAll0.4800.282<.00141view →
UVMDFSTertileIII,IV0.3670.796.00135view →
ACCOSQuartileAll0.2990.788.00327view →
STADOSQuartileIII,IV0.6430.382.00521view →
MESOOSTertileII,III,IV0.2110.435.00919view →
READOSMedianIII,IV0.4290.886.01915view →
UCSOSTertileIV0.2060.675.02412view →
Pink = unfavorable, green = favorable. Showing the 12 strongest of 26 lineages.

RNVU1-27–KICH (DFS)

Kaplan–Meier survival curve for RNVU1-27 RNA-high vs -low samples in KICH.

Open the KICH breakdown →

Exploration