RNVU1-25

Across TCGA pan-cancer cohorts, RNVU1-25 RNA differs between tumor and matched normal tissue in 7 of 18 cancer types tested, making tumor–normal expression one of RNVU1-25’s most consistent transcriptional readouts.

The strongest signal is observed in cholangiocarcinoma (CHOL), where RNVU1-25 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types RNVU1-25 is over-expressed in tumor.

CHOL, COAD, and LUSC are the cancer types where RNVU1-25 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in RNVU1-25 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
CHOL	All	II,III,IV	+0.535	<.001	4	view →
COAD	Male	All	+0.423	.015	3	view →
LUSC	Male	All	+0.278	<.001	3	view →
LUAD	All	All	+0.277	.001	3	view →
ESCA	All	All	+0.752	.001	2	view →
BLCA	All	All	+0.351	.032	2	view →
LIHC	Male	All	+0.206	.013	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 7 strongest of 7 lineages.

RNVU1-25–CHOL

Open the CHOL breakdown →