RNVU1-1

Across TCGA pan-cancer cohorts, RNVU1-1 RNA differs between tumor and matched normal tissue in 10 of 18 cancer types tested, making tumor–normal expression one of RNVU1-1’s most consistent transcriptional readouts.

The strongest signal is observed in colon adenocarcinoma (COAD), where RNVU1-1 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types RNVU1-1 is over-expressed in tumor, although a few such as BRCA and KICH show the opposite, repressed pattern.

COAD, LUAD, and BRCA are the cancer types where RNVU1-1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in RNVU1-1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
COAD	Male	III,IV	+1.203	<.001	9	view →
LUAD	Male	All	+0.929	<.001	7	view →
BRCA	All	III,IV	−1.025	<.001	6	view →
LUSC	All	All	+0.315	.009	4	view →
CHOL	All	All	+1.245	<.001	3	view →
KICH	All	All	−0.431	.006	3	view →
PAAD	All	All	+1.062	.011	2	view →
THCA	All	All	+0.333	.002	2	view →
LIHC	All	All	+0.144	.019	2	view →
STAD	All	IV	+0.490	.039	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 10 strongest of 10 lineages.

RNVU1-1–COAD

Open the COAD breakdown →