RNU7-97P

Across TCGA pan-cancer cohorts, RNU7-97P RNA differs between tumor and matched normal tissue in 4 of 18 cancer types tested, making tumor–normal expression one of RNU7-97P’s most consistent transcriptional readouts.

The strongest signal is observed in breast invasive carcinoma (BRCA), where RNU7-97P RNA is repressed in tumor relative to normal tissue. In most cancer types RNU7-97P is over-expressed in tumor, although a few such as BRCA and KICH show the opposite, repressed pattern.

BRCA, KICH, and LUAD are the cancer types where RNU7-97P tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in RNU7-97P RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
BRCA	All	IV	−1.194	<.001	8	view →
KICH	Female	All	−0.543	.018	2	view →
LUAD	Female	II,III,IV	+0.306	.049	1	view →
LIHC	Male	All	+0.157	.046	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 4 strongest of 4 lineages.

RNU7-97P–BRCA

Open the BRCA breakdown →