RNU7-6P

Across TCGA pan-cancer cohorts, RNU7-6P RNA is linked to patient survival in 8 of 34 cancer types, making it the most broadly survival-associated RNU7-6P data layer.

The strongest signal is observed in bladder urothelial carcinoma (BLCA), where higher RNU7-6P RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated RNU7-6P expression acts as an unfavorable survival marker.

BLCA, BRCA, and THCA are the cancer types where RNU7-6P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
BLCA	DFS	Tertile	All	0.121	0.617	<.001	108	view →
BRCA	DFS	Tertile	All	0.604	0.904	<.001	72	view →
THCA	DFS	Tertile	All	0.049	0.841	<.001	72	view →
COAD	DFS	Tertile	All	0.170	0.790	.002	54	view →
STAD	DFS	Tertile	IV	0.075	0.494	<.001	45	view →
SKCM	OS	Tertile	All	0.242	0.791	<.001	45	view →
UCEC	OS	Tertile	All	0.813	0.927	.001	36	view →
KIRP	OS	Tertile	All	0.590	0.903	.012	9	view →

Pink = unfavorable, green = favorable. Showing the 8 strongest of 8 lineages.

RNU7-6P–BLCA (DFS)

Open the BLCA breakdown →