RNU7-52P

Across TCGA pan-cancer cohorts, RNU7-52P RNA is linked to patient survival in 8 of 34 cancer types, making it the most broadly survival-associated RNU7-52P data layer.

The strongest signal is observed in skin cutaneous melanoma (SKCM), where higher RNU7-52P RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated RNU7-52P expression acts as an unfavorable survival marker, although some lineages such as GBM and ESCA show a favorable association.

SKCM, UVM, and OV are the cancer types where RNU7-52P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
SKCM	DFS	Tertile	All	0.043	0.738	<.001	108	view →
UVM	OS	Tertile	All	0.136	0.919	<.001	90	view →
OV	DFS	Tertile	II,III,IV	0.219	0.542	.002	54	view →
STAD	DFS	Tertile	All	0.459	0.653	.002	36	view →
GBM	OS	Tertile	All	0.919	0.398	.016	18	view →
LGG	DFS	Tertile	All	0.089	0.845	<.001	18	view →
LAML	DFS	Tertile	All	0.084	0.579	<.001	18	view →
ESCA	DFS	Tertile	III,IV	0.744	0.286	.047	6	view →

Pink = unfavorable, green = favorable. Showing the 8 strongest of 8 lineages.

RNU7-52P–SKCM (DFS)

Open the SKCM breakdown →