RNU7-50P

Across TCGA pan-cancer cohorts, RNU7-50P RNA is linked to patient survival in 12 of 34 cancer types, making it the most broadly survival-associated RNU7-50P data layer.

The strongest signal is observed in thyroid carcinoma (THCA), where higher RNU7-50P RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated RNU7-50P expression acts as an unfavorable survival marker, although some lineages such as BRCA and STAD show a favorable association.

THCA, ACC, and HNSC are the cancer types where RNU7-50P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
THCA	DFS	Tertile	III,IV	0.346	0.727	<.001	102	view →
ACC	OS	Tertile	II,III,IV	0.389	0.790	<.001	102	view →
HNSC	OS	Tertile	II,III,IV	0.272	0.732	<.001	66	view →
KIRC	OS	Tertile	All	0.449	0.666	<.001	42	view →
DLBC	OS	Tertile	II,III,IV	0.115	0.839	<.001	36	view →
SKCM	OS	Tertile	IV	0.297	0.777	<.001	30	view →
BLCA	OS	Tertile	IV	0.196	0.622	<.001	27	view →
PAAD	OS	Tertile	All	0.193	0.523	.016	18	view →
LIHC	DFS	Tertile	All	0.227	0.561	.007	18	view →
BRCA	OS	Tertile	III,IV	0.942	0.510	.033	9	view →
STAD	OS	Tertile	IV	0.574	0.213	.013	6	view →
ESCA	DFS	Tertile	II,III,IV	0.405	0.560	.031	4	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 12 lineages.

RNU7-50P–THCA (DFS)

Open the THCA breakdown →