RNU7-2P

Across TCGA pan-cancer cohorts, RNU7-2P RNA is linked to patient survival in 2 of 34 cancer types, making it the most broadly survival-associated RNU7-2P data layer.

The strongest signal is observed in testicular germ cell tumors (TGCT), where higher RNU7-2P RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated RNU7-2P expression acts as an unfavorable survival marker, although some lineages such as ESCA show a favorable association.

TGCT and ESCA are the cancer types where RNU7-2P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
TGCT	DFS	Tertile	All	0.035	0.837	<.001	18	view →
ESCA	OS	Tertile	III,IV	1.000	0.372	.033	12	view →

Pink = unfavorable, green = favorable. Showing the 2 strongest of 2 lineages.

RNU7-2P–TGCT (DFS)

Open the TGCT breakdown →