RNU7-22P

RNA & survival
SurvivalRNAKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, RNU7-22P RNA is linked to patient survival in 4 of 34 cancer types, making it the most broadly survival-associated RNU7-22P data layer.

The strongest signal is observed in breast invasive carcinoma (BRCA), where higher RNU7-22P RNA is associated with worse overall survival. In most high-consensus cancer types, elevated RNU7-22P expression acts as an unfavorable survival marker.

BRCA, KIRC, and ESCA are the cancer types where RNU7-22P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
BRCAOSTertileAll0.3360.924<.00172view →
KIRCDFSTertileIV0.1270.619.00836view →
ESCAOSTertileAll0.1980.872.00336view →
STADDFSTertileAll0.4440.722.0473view →
Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

RNU7-22P–BRCA (OS)

Kaplan–Meier survival curve for RNU7-22P RNA-high vs -low samples in BRCA.

Open the BRCA breakdown →

Exploration