RNU7-21P

Across TCGA pan-cancer cohorts, RNU7-21P RNA is linked to patient survival in 6 of 34 cancer types, making it the most broadly survival-associated RNU7-21P data layer.

The strongest signal is observed in kidney renal papillary cell carcinoma (KIRP), where higher RNU7-21P RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated RNU7-21P expression acts as an unfavorable survival marker.

KIRP, GBM, and STAD are the cancer types where RNU7-21P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRP	DFS	Tertile	All	0.479	0.859	<.001	66	view →
GBM	OS	Tertile	All	0.055	0.416	<.001	45	view →
STAD	DFS	Tertile	IV	0.068	0.480	<.001	36	view →
ESCA	OS	Tertile	II,III,IV	0.377	0.699	.023	18	view →
LAML	DFS	Tertile	All	0.112	0.579	.004	18	view →
LGG	DFS	Tertile	All	0.206	0.757	<.001	9	view →

Pink = unfavorable, green = favorable. Showing the 6 strongest of 6 lineages.

RNU7-21P–KIRP (DFS)

Open the KIRP breakdown →