RNU7-186P

Across TCGA pan-cancer cohorts, RNU7-186P RNA differs between tumor and matched normal tissue in 11 of 18 cancer types tested, making tumor–normal expression one of RNU7-186P’s most consistent transcriptional readouts.

The strongest signal is observed in bladder urothelial carcinoma (BLCA), where RNU7-186P RNA is repressed in tumor relative to normal tissue. In most cancer types RNU7-186P is over-expressed in tumor, although a few such as BLCA and BRCA show the opposite, repressed pattern.

BLCA, BRCA, and KICH are the cancer types where RNU7-186P tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in RNU7-186P RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
BLCA	All	All	−1.017	.001	8	view →
BRCA	All	II,III,IV	−0.500	<.001	8	view →
KICH	All	IV	−1.795	<.001	4	view →
THCA	Female	All	−0.875	<.001	4	view →
COAD	Male	All	−0.335	.006	4	view →
READ	All	III,IV	−0.965	.019	3	view →
KIRP	Male	All	+0.687	.025	3	view →
ESCA	All	II,III,IV	+1.949	<.001	2	view →
UCEC	All	All	−0.476	.029	2	view →
PRAD	All	All	−0.235	.030	2	view →
STAD	Female	III,IV	+2.085	.046	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 11 strongest of 11 lineages.

RNU7-186P–BLCA

Open the BLCA breakdown →