RNU7-180P

RNA — tumor vs normal
Tumor vs NormalRNABox plot · TCGA cohorts

Across TCGA pan-cancer cohorts, RNU7-180P RNA differs between tumor and matched normal tissue in 4 of 18 cancer types tested, making tumor–normal expression one of RNU7-180P’s most consistent transcriptional readouts.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where RNU7-180P RNA is more highly expressed in tumor relative to normal tissue. In most cancer types RNU7-180P is over-expressed in tumor.

HNSC, BRCA, and ESCA are the cancer types where RNU7-180P tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in RNU7-180P RNA (log2); positive values indicate higher expression in tumor. p-values are from the differential-expression test.
LineageGenderStageFold-changepSampling consensus
HNSCMaleIV+0.434.0423view →
BRCAFemaleAll+0.187.0272view →
ESCAFemaleAll+1.053.0051view →
STADMaleAll+0.222.0301view →
Pink = over-expressed in tumor, green = repressed in tumor. Showing the 4 strongest of 4 lineages.

RNU7-180P–HNSC

Tumor-vs-normal expression box plot for RNU7-180P RNA in HNSC.

Open the HNSC breakdown →

Exploration