RNU7-174P

Mutation & survival
SurvivalMutationKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, RNU7-174P Mutation is linked to patient survival in 1 of 34 cancer types, making it a survival-associated RNU7-174P data layer compared with 10 for mass-spec protein.

The strongest signal is observed in lung squamous cell carcinoma (LUSC), where higher RNU7-174P Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated RNU7-174P expression acts as an unfavorable survival marker.

LUSC are the cancer types where RNU7-174P Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
LUSCOSMedianAll0.1560.675.01424view →
Pink = unfavorable, green = favorable. Showing the 1 strongest of 1 lineages.

RNU7-174P–LUSC (OS)

Kaplan–Meier survival curve for RNU7-174P mutant vs wild-type samples in LUSC.

Open the LUSC breakdown →

Exploration