RNU7-174P

Across TCGA patient cohorts, RNU7-174P mutation is significantly associated with the RNA expression of many other genes, with 63 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RNU7-174P-associated genes across cancer lineages are KRTAP9-12P, MTATP6P4, and KRT8P25. Each is linked with RNU7-174P in more than 1 cancer types. Because this analysis shows association rather than direction, both RNU7-174P-to-partner and partner-to-RNU7-174P results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, KRTAP9-12P grouped by RNU7-174P-low versus RNU7-174P-high in LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RNU7-174P→partner) and Y-score (partner→RNU7-174P) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	KRTAP9-12P →	+0.486	+4.453	.008	.006	3	2
SKCM	MTATP6P4 →	+0.091	+6.469	<.001	.001	3	1
SKCM	KRT8P25 →	+0.043	+5.097	<.001	.008	3	1
SKCM	RN7SL706P →	+0.277	+5.097	<.001	.008	3	1
SKCM	TRAJ60 →	+0.702	+5.097	<.001	.008	3	1
SKCM	PALLD-AS1 →	+0.122	+4.979	.005	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 63 associations by consensus.

KRTAP9-12P by RNU7-174P expression — LUAD

Explore this box plot interactively →