RNU7-174P

Across TCGA patient cohorts, RNU7-174P mutation is significantly associated with the total protein of many other genes, with 6 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RNU7-174P-associated genes across cancer lineages are MIG-6, PCNA, and TIGAR. Each is linked with RNU7-174P in more than 1 cancer types. Because this analysis shows association rather than direction, both RNU7-174P-to-partner and partner-to-RNU7-174P results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIG-6 grouped by RNU7-174P-low versus RNU7-174P-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RNU7-174P→partner) and Y-score (partner→RNU7-174P) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	MIG-6 →	+0.130	+3.013	.023	.019	3	1
UCEC	PCNA →	+0.409	+3.000	.001	.037	2	1
UCEC	TIGAR →	+0.244	+3.026	.005	.019	2	1
UCEC	mTOR →	-0.313	-3.000	<.001	.037	1	1
UCEC	p62 Lck ligand →	+0.450	+3.000	.016	.037	1	1
UCEC	Rab25 →	-0.569	-3.000	.002	.037	1	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 6 associations by consensus.

MIG-6 by RNU7-174P expression — UCEC

Explore this box plot interactively →