RNU7-171P

RNA — tumor vs normal
Tumor vs NormalRNABox plot · TCGA cohorts

Across TCGA pan-cancer cohorts, RNU7-171P RNA differs between tumor and matched normal tissue in 8 of 18 cancer types tested, making tumor–normal expression one of RNU7-171P’s most consistent transcriptional readouts.

The strongest signal is observed in lung adenocarcinoma (LUAD), where RNU7-171P RNA is repressed in tumor relative to normal tissue. In most cancer types RNU7-171P is over-expressed in tumor, although a few such as LUAD and LUSC show the opposite, repressed pattern.

LUAD, LUSC, and KICH are the cancer types where RNU7-171P tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in RNU7-171P RNA (log2); positive values indicate higher expression in tumor. p-values are from the differential-expression test.
LineageGenderStageFold-changepSampling consensus
LUADFemaleII,III,IV−1.258<.0018view →
LUSCAllAll−0.673<.0017view →
KICHAllAll−0.799<.0014view →
BLCAAllIV−1.162.0023view →
ESCAAllII,III,IV+1.510.0122view →
UCECAllAll−0.986.0022view →
BRCAAllAll−0.294.0242view →
CHOLFemaleAll+1.156.0431view →
Pink = over-expressed in tumor, green = repressed in tumor. Showing the 8 strongest of 8 lineages.

RNU7-171P–LUAD

Tumor-vs-normal expression box plot for RNU7-171P RNA in LUAD.

Open the LUAD breakdown →

Exploration