RNU7-159P

Across TCGA pan-cancer cohorts, RNU7-159P RNA differs between tumor and matched normal tissue in 6 of 18 cancer types tested, making tumor–normal expression one of RNU7-159P’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where RNU7-159P RNA is repressed in tumor relative to normal tissue. In most cancer types RNU7-159P is over-expressed in tumor, although a few such as KIRC and KIRP show the opposite, repressed pattern.

KIRC, KIRP, and HNSC are the cancer types where RNU7-159P tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in RNU7-159P RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRC	Female	IV	−2.545	<.001	12	view →
KIRP	Female	II,III,IV	−2.392	<.001	11	view →
HNSC	All	II,III,IV	+0.571	.037	4	view →
LUAD	All	All	+0.279	.020	3	view →
KICH	All	All	−0.928	.010	2	view →
LUSC	All	All	+0.586	.012	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 6 strongest of 6 lineages.

RNU7-159P–KIRC

Open the KIRC breakdown →