RNU7-123P

Across TCGA pan-cancer cohorts, RNU7-123P RNA differs between tumor and matched normal tissue in 9 of 18 cancer types tested, making tumor–normal expression one of RNU7-123P’s most consistent transcriptional readouts.

The strongest signal is observed in bladder urothelial carcinoma (BLCA), where RNU7-123P RNA is more highly expressed in tumor relative to normal tissue. In most cancer types RNU7-123P is over-expressed in tumor, although a few such as LUAD and KIRP show the opposite, repressed pattern.

BLCA, CHOL, and LIHC are the cancer types where RNU7-123P tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in RNU7-123P RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
BLCA	Female	III,IV	+1.175	<.001	7	view →
CHOL	All	All	+1.798	<.001	5	view →
LIHC	All	All	+0.462	<.001	5	view →
LUAD	All	III,IV	−0.770	.014	2	view →
STAD	All	All	+0.541	.023	2	view →
KIRP	Male	III,IV	−0.785	.026	1	view →
KICH	All	All	−0.574	.017	1	view →
KIRC	Male	III,IV	−0.520	.011	1	view →
BRCA	All	All	−0.280	.045	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 9 strongest of 9 lineages.

RNU7-123P–BLCA

Open the BLCA breakdown →