Across TCGA pan-cancer cohorts, RNU6V RNA is linked to patient survival in 24 of 34 cancer types, making it the most broadly survival-associated RNU6V data layer.
The strongest signal is observed in adrenocortical carcinoma (ACC), where higher RNU6V RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated RNU6V expression acts as an unfavorable survival marker, although some lineages such as UCS and BLCA show a favorable association.
ACC, COAD, and KICH are the cancer types where RNU6V RNA most reproducibly stratifies survival.
RNA survival associations by lineage
Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.