Across TCGA pan-cancer cohorts, RNU6ATAC4P RNA differs between tumor and matched normal tissue in 3 of 18 cancer types tested, making tumor–normal expression one of RNU6ATAC4P’s most consistent transcriptional readouts.

The strongest signal is observed in lung squamous cell carcinoma (LUSC), where RNU6ATAC4P RNA is repressed in tumor relative to normal tissue. In most cancer types RNU6ATAC4P is over-expressed in tumor, although a few such as LUSC and COAD show the opposite, repressed pattern.

LUSC, COAD, and KIRC are the cancer types where RNU6ATAC4P tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in RNU6ATAC4P RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
LUSC	All	All	−0.141	.013	2	view →
COAD	All	All	−0.133	.019	2	view →
KIRC	Male	All	+0.060	.026	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 3 strongest of 3 lineages.

Exploration

Same gene, other analysis: RNU6ATAC4P RNA expression & survival · all RNU6ATAC4P data types